During a taxonomic treatment of Connarus L. (Connaraceae) in the Brazilian Amazon, two new species of the genus were identified: Connarus manausensis and Connarus ramiflorus . Descriptions and illustrations of the new taxa are provided, including information on their habitat, distribution, and phenology, along with a key to recognize the species of Connarus occurring in the Brazilian Amazon. The new species have only been found in single locations of Amazonas state (Brazil), but our hypothesis is that their distribution is poorly understood due to the scarcity of botanical data in the study area.